Isos ancient site was the place where Persians and Macedonian Empire made a war. Macedonians, Alexander the Great, won the war. They had the chance to move to Asia. Isos ancient site is located at Erzin county of Osmaniye province.
Alexander the Great had faced to Persian Empire when he moved to Asia. Both sides had met in front of Isos ancient site. Alexander the Great won the battle and had an advantage for military campaign to Asia.
Macedonians and Persians were important states of ancient era.